Technical scientific documents 
Synthetic Haptens and Monoclonal Antibodies to the Cyanotoxin Anatoxin-a.
Guillermo Quiñones-Reyes G, Consuelo Agulló, Josep V. Mercader, Antonio Abad-Somovilla, Antonio Abad-Fuentes.
Angewandte Chemie International Edition, 58(27), 9134-9139, 2019.
doi: 10.1002/anie.201904002.
Study of Epitope Imprinting for Small Templates: Preparation of NanoMIPs for Ochratoxin A.
Daniel Lopez-Puertollano, Todd Cowen, Álvaro García-Cruz, Elena Piletska, Antonio Abad-Somovilla, Antonio Abad-Fuentes, Sergey Piletsky.
CHEMNANOMAT, 5(5), 651-657, 2019
doi: 10.1002/cnma.201900050
Combined heterologies for monoclonal antibody-based immunoanalysis of fluxapyroxad.
Eric Ceballos-Alcantarilla, Daniel López-Puertollano, Consuelo Agulló, Antonio Abad-Fuentes, Antonio Abad-Somovilla, Josep V. Mercader.
Analyst, 143(23), 5718-5727, 2018
doi: 10.1039/c8an01771a
Rationally designed haptens for highly sensitive monoclonal antibody-based immunoanalysis of fenhexamid.
Francesc A. Esteve-Turrillas, Consuelo Agulló, Josep V. Mercader, A. Abad-Somovilla, A. Abad-Fuentes
Analyst, 143(17), 4057-4066, 2018
doi: 10.1039/c8an00827b
Novel haptens and monoclonal antibodies with subnanomolar affinity for a classical analytical target, ochratoxin A
Daniel López-Puertollano, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Scientific Reports, 8, Article number: 9761, 2018
doi: 10.1038/s41598-018-28138-x
Immunochemical rapid determination of quinoxyfen, a priority hazardous pollutant.
HadynDuncan, AntonioAbad-Somovilla,, AntonioAbad-Fuentes, ConsueloAgulló, Josep V. Mercader
Chemosphere, 211, 302-307, 2018
doi: 10.1016/j.chemosphere.2018.07.166
Highly sensitive monoclonal antibody-based immunoassays for boscalid analysis in strawberries
Francesc A.Esteve-Turrillas, Josep V.Mercader, ConsueloAgulló, AntonioAbad-Somovilla, AntonioAbad-Fuentes
Food Chemistry, 267, 2-9, 2018
doi: 10.1016/j.foodchem.2017.06.013
Hapten Design and Antibody Generation for Immunoanalysis of Spirotetramat and Spirotetramat-enol
Ramón E. Cevallos-Cedeño, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes , Josep V. Mercader
ACS Omega, 3(9), 11950-11957, 2018
doi: 10.1021/acsomega.8b01784
Enlace: https://pubs.acs.org/doi/10.1021/acsomega.8b01784
A unified approach to the synthesis of both enantiomers of anatoxin-a and homoanatoxin-a cyanotoxins
Luis G. Addante-Moya, Consuelo Agulló; Guillermo Quiñones-Reyes, Josep V. Mercader, Antonio Abad-Fuentes, Antonio Abad-Somovilla
Tetrahedron, 74(38), 5022-5031, 2018
doi: https://doi.org/10.1016/j.tet.2018.04.057
Highly sensitive monoclonal antibody-based immunoassays for boscalid analysis in strawberries
Francesc. A. Esteve-Turrillas, Josep. V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Chemistry, en prensa, 2017
doi: 10.1016/j.foodchem.2017.06.013
Fluxapyroxad Haptens and Antibodies for Highly Sensitive Immunoanalysis of Food Samples
Josep. V. Mercader; Antonio Abad-Somovilla; Consuelo Agulló; Antonio Abad-Fuentes.
Journal of Agricultural and Food Chemistry, 65(42), 9333-9341, 2017
doi: 10.1021/acs.jafc.7b03199
A class-selective immunoassay for simultaneous analysis of anilinopyrimidine fungicides using a rationally designed hapten
Francesc A Esteve-Turrillas, Josep V Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Analyst, 142, 3975-3985, 2017
doi: 10.1039/C7AN01138E
Protein-Free Hapten-Carbon Nanotube Constructs Induce the Secondary Immune Response
Eric Ceballos-Alcantarilla, Antonio Abad-Somovilla, Consuelo Agulló, Antonio Abad-Fuentes, Josep V. Mercader
Bioconjugate Chemistry, 28(6) 1630-1638, 2017
doi: 10.1021/acs.bioconjchem.6b00653
High-affinity Antibodies from a Full Penthiopyrad-mimicking Hapten and Heterologous Immunoassay Development for Fruit Juice Analysis
Eric Ceballos-Alcantarilla, Consuelo Agulló, Antonio Abad-Fuentes, Mónica Escamilla-Aguilar, Antonio Abad-Somovilla; Josep V. Mercader.
Food Analytical Methods, 10(12), 4013-4023, 2017
doi. 10.1007/s12161-017-0974-3
Highly selective solid-phase extraction sorbents for chloramphenicol determination in food and urine by ion mobility spectrometry
Sergio Armenta, Miguel de la Guardia, Antonio Abad-Fuentes, Antonio Abad-Somovilla, Francesc. A. Esteve-Turrillas .
Analytical Bioanalytical Chemistry, 408(29), 8559-8567, 2016
doi: 10.1007/s00216-016-9995-9
Fungicide multiresidue monitoring in international wines by immunoassays
Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Somovilla, Josep V. Mercader, Antonio Abad-Fuentes
Food Chemistry, 196, 1279–1286, 2016
doi: 10.1016/j.foodchem.2015.10.102
Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis
Ceballos-Alcantarilla, C. Agulló, A. Abad-Fuentes, A. Abad-Somovilla, J. V. Mercader
RSC Advances, 5, 51337-51341, 2015
doi: 10.1039/C5RA09124A
Ready Access to Proquinazid Haptens via Cross-Coupling Chemistry for Antibody Generation and Immunoassay Development
Francesc A. Esteve-Turrillas, Josep V. Mercader, Javier Parra, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
PLoS ONE 10(7): e0134042, 2015
doi:10.1371/journal.pone.0134042
Determination of succinate-dehydrogenase-inhibitor fungicide residues in fruits and vegetables by liquid chromatography–tandem mass spectrometry
Antonio Abad-Fuentes, Eric Ceballos-Alcantarilla, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Francesc A. Esteve-Turrillas
Analytical and Bioanalytical Chemistry, 407(14), 4207–4211, 2015
doi: 10.1007/s00216-015-8608-3
Site-heterologous haptens and competitive monoclonal antibody-based immunoassays for pyrimethanil residue analysis in foodstuffs
Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
LWT – Food Science and Technology, 63(1), 604-611, 2015
doi: 10.1016/j.lwt.2015.03.074
Moiety and linker site heterologies for highly sensitive immunoanalysis of cyprodinil in fermented alcoholic drinks
Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Control, 50, 393–400, 2015
doi: 10.1016/j.foodcont.2014.09.023
Off-line coupling of multidimensional immunoaffinity chromatography and ion mobility spectrometry: A promising partnership
Sergio Armenta, Miguel de la Guardia, Antonio Abad-Fuentes, Antonio Abad-Somovilla, Francesc A. Esteve-Turrillas
Journal of Chromatography A, 1426, 110-117, 2015
doi: 10.1016/j.chroma.2015.11.050
Monoclonal antibody-based immunoassays for cyprodinil residue analysis in QuEChERS-based fruit extracts
Francesc A. Esteve-Turrillas, Antonio Abad-Somovilla, Guillermo Quiñones-Reyes, Consuelo Agulló, Josep V. Mercader, Antonio Abad-Fuentes
Food Chemistry, 187, 530-536, 2015
doi: 10.1016/j.foodchem.2015.04.119
Development of a sensitive and specific enzyme-linked immunosorbent assay for the determination of fludioxonil residues in fruit juices
Josep V. Mercader, Antonio Abad-Fuentes, Consuelo Agulló, Antonio Abad-Somovilla and Francesc A. Esteve-Turrillas
Analytical Methods, 6, 8924-8929, 2014
doi: 10.1039/C4AY01756K
Immunoassays for trifloxystrobin analysis. Part II. Assay development and application to residue determination in food
Josep V. Mercader, Rosario López-Moreno, Francesc A. Esteve-Turrillas, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Chemistry, 162, 41-46, 2014
doi: 10.1016/j.foodchem.2014.04.053
Immunoassays for trifloxystrobin analysis. Part I. Rational design of regioisomeric haptens and production of monoclonal antibodies
Rosario López-Moreno, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Chemistry, 152, 230-236, 2014
doi: 10.1016/j.foodchem.2013.11.150
Haptens, bioconjugates, and antibodies for penthiopyrad immunosensing
Eric Ceballos-Alcantarilla, Antonio Abad-Fuentes, Vincenzo Aloisio, Consuelo Agulló, Antonio Abad-Somovilla, Josep V. Mercader
Analyst, 139, 5358-5361, 2014
doi: 10.1039/C4AN00828F
Design and development of heterologous competitive immunoassays for the determination of boscalid residues
Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Javier Marzo, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Analyst, 139, 3636-3644, 2014
doi: 10.1039/C3AN01104F
Sensitive Monoclonal Antibody-Based Immunoassays for Kresoxim-methyl Analysis in QuEChERS-Based Food Extracts
Josep V. Mercader, Rosario López-Moreno, Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Somovilla,,Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 62(13), 2816–2821, 2014
doi: 10.1021/jf500287
Structure–immunogenicity relationship of kresoxim-methyl regioisomeric haptens
Rosario López-Moreno, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Organic & Biomolecular Chemistry, 11, 7361-7371, 2013,
doi: 10.1039/C3OB41570H
Immunoassays for pyraclostrobin analysis in processed food products using novel monoclonal antibodies and QuEChERS-based extracts
Josep V. Mercader, Consuelo Agulló, Francesc A. Esteve-Turrillas, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Control, 32(1), 42-48, 2013
doi: 10.1016/j.foodcont.2012.12.003
Carbon nanotube-protein carriers enhance size-dependent self-adjuvant antibody response to haptens
Javier Parra, Antonio Abad-Somovilla, Josep V. Mercader, T. Andrew Taton, Antonio Abad-Fuentes
Journal of Controlled Release, 170(2), 242–251, 2013
doi: 10.1016/j.jconrel.2013.05.019
Mepanipyrim haptens and antibodies with nanomolar affinity
Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Analyst, 138, 3360-3364, 2013
doi: 10.1039/C3AN00228D
Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron
Celia Suárez-Pantaleón, Jan Wichers, Antonio Abad-Somovilla, Aart van Amerongen, Antonio Abad-Fuentes
Biosensors and Bioelectronics, 42, 170–176, 2013
doi: /10.1016/j.bios.2012.11.001
Development and validation of a direct competitive monoclonal antibody-based immunoassay for the sensitive and selective analysis of the phytoregulator forchlorfenuron
Celia Suárez-Pantaleón, Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla and Antonio Abad-Fuentes
Analytical and Bioanalytical Chemistry, 403, 2019-2026, 2012
doi: 10.1007/s00216-012-5991-x
Development of monoclonal antibody-based competitive immunoassays for the detection of picoxystrobin in cereal and oilseed flours
Josep V. Mercader, Javier Parra, Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Food Control, 26(1), 162–168, 2012
doi: 10.1016/j.foodcont.2012.01.021
Synthesis of azoxystrobin transformation products and selection of monoclonal antibodies for immunoassay development
Javier Parra, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Toxicology Letters, 210(2), 240–247, 2012
doi: 10.1016/j.toxlet.2011.07.030
Development of competitive enzyme-linked immunosorbent assays for boscalid determination in fruit juices
Antonio Abad-Fuentes, Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Somovilla, Josep V. Mercader
Food Chemistry, 135, 276-284, 2012
doi: 10.1016/j.foodchem.2012.04.090
Generation of anti-azoxystrobin monoclonal antibodies from regioisomeric haptens functionalized at selected sites and development of indirect competitive immunoassays
Javier Parra, Josep V. Mercader, Consuelo Agulló Antonio Abad-Somovilla, Antonio Abad-Fuentes
Analytica Chimica Acta, 715, 105-112, 2012
doi: 10.1016/j.aca.2011.12.014
Antibody generation and immunoassay development in diverse formats for pyrimethanil specific and sensitive analysis
Josep V. Mercader, Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Analyst, 137, 5672-5679, 2012,
doi: 10.1039/C2AN35801H
Immunoreagent Generation and Competitive Assay Development for Cyprodinil Analysis
Francesc A. Esteve-Turrillas, Consuelo Agulló, Antonio Abad-Fuentes, Antonio Abad-Somovilla, Josep V. Mercader
Journal of Agricultural and Food Chemistry, 60(19), 4803–4811, 2012
doi: 10.1021/jf300319n
Forchlorfenuron-mimicking haptens: from immunogen design to antibody characterization by hierarchical clustering analysisCelia Suárez-Pantaleón, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla,, Antonio Abad-Fuentes
Organic & Biomolecular Chemistry, 9, 4863-4872, 2011,
doi: 10.1039/C1OB05190C
Synthesis of site-heterologous haptens for high-affinity anti-pyraclostrobin antibody generation
Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Organic & Biomolecular Chemistry, 9, 1443-1453, 2011
doi: 10.1039/C0OB00686F
Development of immunoaffinity columns for pyraclostrobin extraction from fruit juices and analysis by liquid chromatography with UV detection
Francesc A. Esteve-Turrillas, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Chromatography A, 1218(30), 4902–4909, 2011
doi: 10.1016/j.chroma.2011.03.022
Concise and modular synthesis of regioisomeric haptens for the production of high-affinity and stereoselective antibodies to the strobilurin azoxystrobin
Javier Parra, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Fuentes, Antonio Abad-Somovilla
Tetrahedron, 67(15), 624-635, 2011
doi: 10.1016/j.tet.2010.11.054
Exploring alternative hapten tethering sites for high-affinity anti-picoxystrobin antibody generation
Javier Parra, Francesc A. Esteve-Turrillas, Antonio Abad-Somovilla, Consuelo Agulló, Josep V. Mercader, Antonio Abad-Fuentes
Analytical Biochemistry, 416, 82-91, 2011
doi: 10.1016/j.ab.2011.05.016
Hapten synthesis, monoclonal antibody generation, and development of competitive immunoassays for the analysis of picoxystrobin in beer
Francesc A. Esteve-Turrillas, Javier Parra, Antonio Abad-Fuentes, Consuelo Agulló, Antonio Abad-Somovilla, Josep V. Mercader
Analytica Chimica Acta, 682 (1–2), 93–103, 2010
doi: 10.1016/j.aca.2010.09.042
Hapten Synthesis and Polyclonal Antibody-Based Immunoassay Development for the Analysis of Forchlorfenuron in Kiwifruit
Celia Suárez-Pantaleón, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 58(15), 8502–8511, 2010
doi: 10.1021/jf101660z
Production and Characterization of Monoclonal and Polyclonal Antibodies to Forchlorfenuron
Celia Suárez-Pantaleón, Josep V. Mercader, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 56(23), 11122–11131, 2008
doi: 10.1021/jf802261x
Production and Characterization of Monoclonal Antibodies Specific to the Strobilurin Pesticide Pyraclostrobin
Josep V. Mercader, Celia Suárez-Pantaleón, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 56(17), 7682–7690, 2008,
doi: 10.1021/jf801340u
Hapten Synthesis and Monoclonal Antibody-Based Immunoassay Development for Detection of the Fungicide Trifloxystrobin
Josep V. Mercader, Celia Suárez-Pantaleón, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 56(8), 2581–2588, 2008
doi: 10.1021/jf800157s
Hapten Synthesis and Monoclonal Antibody-Based Immunoassay Development for the Detection of the Fungicide Kresoxim-methyl
Josep V. Mercader, Celia Suárez-Pantaleón, Consuelo Agulló, Antonio Abad-Somovilla, Antonio Abad-Fuentes
Journal of Agricultural and Food Chemistry, 56(5), 1545–1552, 2008
doi: 10.1021/jf800157s